Unsubstituted Phenols
Medchemexpress LLC (+)-Tyrphostin B44 | 133550-37-5 | MFCD00209855 | 97.0% | 308.33 g/mol | C18H16N2O3 | 100 MG
(+)-Tyrphostin B44 is a small-molecule EGFR inhibitor with reported antitumor activity, supplied as a light yellow to yellow solid with molecular formula C18H16N2O3 and high purity for research use. The compound is soluble in DMSO and manufacturer guidance provides recommended in vivo formulation protocols and storage conditions for maintaining stability.
- Acts as an EGFR inhibitor with antitumor activity.
- High purity suitable for research applications.
- Light yellow to yellow solid appearance.
- Soluble in DMSO at concentrations ≥100 mg/mL for in vitro use.
- Includes recommended in vivo formulation protocols for administration.
- Requires cold storage to maintain stability.
Selleck Chemical LLC AMI-1 (free acid) S5445-25mg
AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3 0 M and 8 8 M for yeast Hmt1p and human PRMT1 respectively
Medchemexpress LLC 7,4'-Dihydroxyflavone | 2196-14-7 | 5 MG
7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from *Glycyrrhiza uralensis*. It functions as an eotaxin/CCL11 inhibitor and a CBR1 inhibitor with an IC50 of 0.28 μM. This compound has shown the ability to consistently suppress eotaxin production and prevent the paradoxical adverse effects of dexamethasone on eotaxin production.
- Inhibits MUC5AC gene expression and mucus production and secretion.
- Regulates NF-κB, STAT6, and HDAC2.
- Decreases phorbol 12-myristate 13-acetate (PMA) stimulated MUC5AC gene expression.
- Reduces mucus production in NCI-H292 human airway epithelial cells with an IC50 value of 1.4 μM.
![eMolecules Medchem Express / A-769662 / 5mg / 446270964 / HY-50662 / / 844499-71-4 / [null] / 360.390 / C20H12N2O3S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502447564.PNG-250.jpg)
eMolecules Medchem Express / A-769662 / 5mg / 446270964 / HY-50662 / / 844499-71-4 / [null] / 360.390 / C20H12N2O3S
Medchem Express / A-769662 / 5mg / 446270964 / HY-50662 / / 844499-71-4 / [null] / 360.390 / C20H12N2O3S
Enzo Life Sciences Tyrphostin 1 (100mg). CAS: 2826-26-8
An inactive tyrphostin, which may be used as a negative control. Purity: ≥99%. Solubility: Soluble in 100% ethanol (25mg/ml, warm) or DMSO (25mg/ml). Long Term Storage: Ambient.
Medchemexpress LLC HY-111285 5mg Medchemexpress, HAMNO CAS:138736-73-9 Purity:>98%
Medchemexpress, HY-111285 5mg HAMNO CAS:138736-73-9 HAMNO is a novel protein interaction inhibitor of replication protein A ( RPA ). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Suzetrigine phenol | 2649467-91-2 | 99.4% | 459.37 | 25 MG
Suzetrigine phenol is the phenolate form of the sodium channel modulator Suzetrigine. Suzetrigine is an orally active and highly selective inhibitor of NaV1.8, making it suitable for research into neurological and eye/ear diseases.
- Phenolate form
- Orally active and highly selective inhibitor of NaV1.8
- Supports neurological disease research
- Supports eye or ear disease research
Medchemexpress LLC Tyrphostin AG30 | 122520-79-0 | MFCD09739079 | 99.7% | 205.17 g·mol⁻1 | C10H7NO4 | 100 MG
Tyrphostin AG30 is a small-molecule inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase used in research to probe EGFR/c-ErbB signaling and STAT5 activation. It is supplied as a light yellow solid with high chemical purity and defined storage recommendations for powder and solutions.
- High purity (99.7%), for consistent experimental results.
- Molecular weight 205.17 g·mol⁻1 and formula C10H7NO4.
- Potent and selective inhibitor of EGFR tyrosine kinase.
- Solid, light yellow to yellow appearance, suitable for handling and formulation.
- Recommended storage: powder -20°C (long-term) or 4°C (short-term); solutions -80°C (long-term).
- Provided as a 100 mg research reagent for laboratory use.
Medchemexpress LLC Pentanoic acid, 2-[(2S,4S)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[ | 56124-62-0 | MFCD01939322 | 99.6% | C34H36F3NO13 | 10MG
Valrubicin is an anthracycline chemotherapy agent provided for research use. It inhibits TPA- and PDBu-induced protein kinase C (PKC) activation with reported IC50 values of 0.85 μM and 1.25 μM, and demonstrates antitumor and anti-inflammatory activity in preclinical studies.
- Inhibits TPA- and PDBu-induced protein kinase C activation (IC50 0.85 μM and 1.25 μM).
- Exhibits antitumor and anti-inflammatory activity in preclinical models.
- Provided as a research-grade small molecule for biochemical and cellular assays.
- High purity suitable for analytical applications (purity 99.6% by LCMS).
- Available in small pack sizes suitable for assay development and reference standards.
Medchemexpress LLC Peldesine dihydrochloride | 2772702-10-8 | MFCD32878297 | 99.3% | 314.17 g/mol | C12H13Cl2N5O | 10 MG
Peldesine dihydrochloride is the dihydrochloride salt of a potent purine nucleoside phosphorylase (PNP) inhibitor used in preclinical biochemical and pharmacological research. It exhibits low-nanomolar PNP inhibition across species and suppresses T-cell proliferation, supporting studies in T-cell lymphoma, psoriasis, and HIV-related immunology.
- Potent PNP inhibition with low-nanomolar IC50s for human, rat, and mouse.
- Inhibits T-cell proliferation (IC50 ~800 nM), useful for immunology studies.
- High purity (~99.3%) suitable for research applications.
- Molecular weight 314.17 g/mol and solid, white to off-white appearance.
- Available in small research pack sizes and as DMSO solution formats for assays.
Medchemexpress LLC Numidargistat dihydrochloride | 99.8% | 360.04 g/mol | C11H24BCl2N3O5 | 50 MG
Numidargistat dihydrochloride is a small-molecule arginase inhibitor supplied for research use in immuno-oncology and metabolic enzyme studies. It shows low-nanomolar inhibition of human arginase isoforms and has been used to modulate the tumor microenvironment by reducing myeloid cell-mediated immune suppression. The dihydrochloride salt is provided to improve handling and solubility for in vitro and in vivo experiments.
- Potent arginase inhibition with low-nanomolar activity.
- Used to modulate tumor immune microenvironment in research models.
- Dihydrochloride salt form supports improved solubility and handling.
- High reported purity for research applications (reported ≈99.8%).
- Available in small research quantities suitable for preclinical studies.